My tribute to one of William S. Burroughs' 1960s cutup novels -- my first experience reading him was the Nova Trilogy with one of the three being The Ticket that Exploded. Therefore, it is a cutup Negroni of sorts that is rough around the edges (though no longer a Negroni but something parallel).
1/2 oz Mezcal
1/2 oz Funky Jamaican Rum (such as Smith & Cross)
1 oz Lillet Blanc or Cocchi Americano
1/2 oz Campari
1/2 oz Benedictine
Stir with ice, strain into a cocktail coupe, and garnish with an orange twist.